Hypomagnesaemia causing myopathy and hypocalcaemia in an alcoholic.

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Hypomagnesaemia causing myopathy and hypocalcaemia in an alcoholic.

A well-nourished alcoholic patient developed a subacute myopathy which responded rapidly to correction of severe hypomagnesaemia. The finding of profound hypocalcaemia prompted the measurement of serum magnesium. Magnesium deficiency should be looked for in any alcoholic patient with a myopathy as the prognosis seems better than in many other forms of alcoholic myopathy. Correction of the magne...

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Hypomagnesaemia with Secondary Hypocalcaemia

In 1965, Paunier et al. described a child of 6 weeks who had generalized convulsions and tetany, associated with low serum magnesium and calcium levels. Magnesium therapy stopped the tetany and established a normal serum calcium level. Similar cases were later reported by Salet et al. (1966), Friedman, Hatcher, and Watson (1967), and Skyberg et al. (1967). Most of these authors suggested that t...

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New TRPM6 mutation and management of hypomagnesaemia with secondary hypocalcaemia.

BACKGROUND TRPM6 gene mutation has been reported to cause hypomagnesemia with secondary hypocalcemia (HSH). However, the genotype-phenotype correlation for TRPM6 gene mutations has not been clarified. OBJECTIVE To elucidate the factors underlying the severe neurological complications in HSH and evaluate the potential association between the location of TRPM6 gene mutations and clinical data o...

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Proton pump inhibitor-induced hypomagnesaemia and hypocalcaemia: case review.

Proton pump inhibitor (PPI)-induced hypomagnesaemia is a rare but serious adverse effect of a widely prescribed medication. It has become an increasingly recognised complication since 2006, with the U.S. Food and Drug Administration issuing a warning for this risk with regards to long-term PPI use. We present the case of PPI-associated hypomagnesaemia and hypocalcaemia. A 91 year old male prese...

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RYR1 causing distal myopathy

BACKGROUND Congenital myopathies due to ryanodine receptor (RYR1) mutations are increasingly identified and correlate with a wide range of phenotypes, most commonly that of malignant hyperthermia susceptibility and central cores on muscle biopsy with rare reports of distal muscle weakness, but in the setting of early onset global weakness. METHODS We report a case of a patient presenting with...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1987

ISSN: 0032-5473

DOI: 10.1136/pgmj.63.742.665